CURRENT RESEARCH PROJECTS ONGOING:


- Subchondroplasty Procedure and its benefits for treatement of bone marrow lesions

- MRI assessment of ACL reconstruction and cartilage health over time

- Utilization, safety and effectiveness of regional anesthesia for ACL surgery and clnical outcomes



Published Journal Articles and Abstracts:



Defea, K.A., Vaughn, Z.D., O’Bryan, E.M., Nishijima, D., Dery, O., Bunnett, N.W. “The Proliferative and Antiapoptotic Effects of Substance P are Facilitated by Formation

        of a Beta- Arrestin-Dependent Scaffolding Complex.”  Proceedings of the National Academy of the United States of America.  Sept., 2000. 97 (20): 11086-11091.

Dery, Olivier; Grady, Eileen; Schmidlin, Fabien; Lovett, Michelle; Vaughn, Zackary; Bunnett, Nigel. “Heterologous Regulation of Signaling and Trafficking of the

        Neurokinin-1 and Neurokinin-3 Receptors.”  Regulatory Peptides. Oct., 2000. 94 (1-3): 29.

Schmidlin, Fabien; Defea, Kathryn; Dery, Olivier; Lovett, Michelle; Vaughn, Zackary; Grady, Eileen; Bunnett, Nigel.  “Dynamin, B-arrestin and rab5a Mediated Trafficking

        and Signalling of the Neurokinin-1 Receptor (NK-1R).”  Regulatory Peptides.  Oct., 2000.  94 (1-3): 17.

Schmidlin, Fabien; Dery, Olivier; Lovett, Michelle; Vaughn, Zackary; Defea, Kathryn; Grady, Eileen; Bunnett, Nigel.  “Rab5A and Dynamin GTPases Mediate Substance P

        (SP)-Induced Trafficking of the Neurokinin-1 Receptor (NK1R).”  Gastroenterology.  April, 2000.  118 (4): A180.

Vaughn, Zackary D., Johnson, Frank E., Beretvas, R. Ivan. “Laparoscopic Adrenalectomy for Conn’s Syndrome Complicated by Ipsilateral Pelvic Kidney.” Surgical

        Endoscopy. Aug., 2004.18 (10): 1539.

Hsu AR, Vaughn Z, and Huddleston JI. Catastrophic Failure of a Porous-Coated Acetabular Cup due to Bead Shedding. A Case Report. Hip International. Oct-Dec 2009.

        19(4):392-395.

Vaughn, Zackary D; Schmidt, Josh; Lindsey, Derek; Dragoo, Jason.  “Biomechanical Evaluation of a one-stage ACL Revision Technique Using a Structural Bone Void

        Filler for Femoral Fixation.” Arthroscopy Sept. 2009: 25(9)1101-1108.

Vaughn, Zackary D; Safran, Marc R. “Arthroscopic Femoral Osteoplasty/Chilectomy for CAM-type Femoroacetabular Impingement in the Athlete”.  Sports Medicine and

        Arthroscopy Review. 2010.

Dragoo, Jason; Miller, Matthew; Vaughn, Zackary; Handley, Elizabeth. “Resoration of Normal Knee Volume Using Selected Arthroscopic Releases.”  Amer J of Sports Med

        2010.

Safran, MR; Lopomo, N; Zaffagnini, S; Vaughn, ZD; Lindsey, DP; Gold, G; Bignozzi, S; Giordano, G;Marcacci, M.  “In Vitro Analysis of Peri-Articular Soft Tissues Passive         

        Constraining Effect on Hip Kinematics and Joint Stability. Knee Surg Sports Traumatol Arthrosc. June 2012.

Tse, BK; Vaughn, ZD; Lindsey, DP; Dragoo, JL.  “Evaluation of a one-stage ACL revision technique using bone void filler after cyclic loading.” Knee. Aug 2012; 19 (4).

          

Conference Presentations of Published Abstracts

    (poster or podium by Vaughn or co-author):



Defea, K.A., Vaughn, Z.D., Dery, O., Bunnett, N.W.  “B-Arrestin-Dependent Endocytosis of the Neurokinin 1 Receptor (NK1R) is Required for Activation of P42/44 MAP

        Kinases.” Gastroenterology. April, 2000.  118 (4): A87.

            Digestive Disease Week (DDW) and the 101st Annual Meeting of the American         

            Gastroenterological Association (AGA).  

            San Diego, California, May 2000

            Poster Presented by Vaughn

Vaughn Z.D., Johnson, F.E., Beretvas, R.I.  “Conn’s Syndrome Treated with Laparoscopic Adrenalectomy Complicated by Ipsilateral Congenital Pelvic Kidney.” Surgical            

         Endoscopy.  March 2003. 17 (Suppl): S287.

            Society of American Gastrointestinal Endoscopic Surgeons (SAGES).

            Los Angeles, California, March 2003

            Poster Presented by Vaughn

Beretvas, R. Ivan, Vaughn, Zackary D., Johnson, Frank E.  “Laparoscopic Adrenalectomy with Ipsilateral Pelvic Kidney.”

            (Training Video) American College of Surgeons; the 89th Clinical Congress

            Chicago, Illinois, October 2003.  

            Presented by Beretvas                                  

Safran, Marc; Zaffagnini, Stephano; Lopomo, Nicoli; Vaughn, Zackary; Lindsey, Derek; Gold, Garry et al. “The Influence of Soft Tissues on Hip Joint Kinematics: An In

        Vitro Computer Assisted Anaylsis.”

            Orthopaedic Research Society, 55th Annual Meeting

            Las Vegas, Nevada, February 2009

            Presented by Safran


Podium Presentations and Lectures:



“Hip arthroscopy and the Acetabular Labrum.”

            Stanford University Department of Orthopeadic Surgery GRAND ROUNDS

            Palo Alto, California, March 2008

“Revision ACL Reconstructions: A biomechanical evaluation of fixation strength and a novel technique for one-stage revisions.”

            Northern California Chapter of the Western Orthopaedic Association

            Sonoma, California, November 2007

            Winner Best Resident Research Paper

                &

            American Academy of Orthopaedic Surgeons (AAOS)

            San Francisco, California February 2008

                &

            OREF Resident Research Symposium

            University of California, San Francisco, April 2009

“Biomechanical Evaluation of a one-stage ACL Revision Technique Using a Structural Bone Void Filler for Femoral Fixation.”

            Stanford University Department of Orthopaedic Surgery Disputation Day

            Palo Alto, California June 2009

“Shoulder Pathology: Labral Injuries, SLAP Lesions, and Biceps Tendon Injury”

                                Stanford University Sports Medicine Conference Lecture Series

                                October 2007

“Groin pain in the Athlete”

                                Stanford University Sports Medicine Conference Lecture Series

                                August 2009

“Posterior Shoulder Instability”

                                Stanford University Sports Medicine Conference Lecture Series

                                October 2009

“Lis Franc Injuries and Tarsal Coalitions in Athletes”

                                Stanford University Sports Medicine Conference Lecture Series

                                December 2009

“Patellar Instability”

                                Stanford University Sports Medicine Conference Lecture Series

                                February 2010

“Knee Ligament Injuries”

                                Stanford University

                                Physical Medicine / Rehabilitation Residency Educational Lecture Series

                                March 2010

“Partial Rotator Cuff Tears”

                                Stanford University Sports Medicine Conference Lecture Series

                                April 2010

“Spondyolysis and Spondylolisthesis in Athletes”

                                Stanford University Sports Medicine Conference Lecture Series

                                June 2010

“Common Hip Problems: Diagnosis and Treatment”

                                BEST Physical Therapy lecture series

                                July 2010

“Advances in the Treatment of Hip Pain with Arthroscopic Techniques”

                                Physical Therapy of Los Gatos

                                December 2010

“Advancements in the Treatment of Shoulder Injuries”

                                BEST Physical Therapy - Almaden Branch

                                February 2011

“High Tibial Osteotomy”

                                Stanford University Department of Orthopaedic Surgery Grand Rounds 2012

"Cartilage Restoration"

                                Stanford University Department of Orthopaedic Surgery Grand Rounds 2013

"Meniscus Repair - Is there a better method?"

                                Stanford University Department of Orthopaedic Surgery Grand Rounds 2015



Textbook Chapters:



Zackary D. Vaughn, MD and Marc R. Safran, MD. “Diagnostic Hip Arthroscopy: Set-up, Equipment, and Positioning – The Supine Approach”

            In “Surgical Techniques in Hip Arthroscopy and Joint Preservation Surgery”; Elsevier Publication

Zackary D. Vaughn, MD; Ken Hunt, MD and Marc R. Safran, MD.  “Ankle Arthroscopy.”

            In “Arthroscopy Primer”, Elsevier Publication

Zackary D. Vaughn, MD; Marc R. Safran, MD. “Femoroacetabular Impingement”

            In “Master Techniques in Orthopaedic Surgery – Sports Medicine”. Lippincott, William and Wilkins Publication



Research Grants Filed:Orthopaedic Research and Education Foundation:  



OREF/DePuy Orthopaedic Resident Educational Grant.  Evaluation of Wrist Kinematics in the Elite Golf Swing. Principal Investigator: Zackary D. Vaughn, MD.  Mentor: Amy

            Ladd, MD (Stanford University Hand And Upper Extremity Surgery)


PUBLICATIONS AND PRESENTATIONS

Zack Vaughn, MD


555 Knowles Drive Suite 201 Los Gatos, California, 95032  Office: (408) 866-6651 Fax: (408) 866-6681

zvaughn@stanford.edu