CURRENT RESEARCH PROJECTS ONGOING:
- Subchondroplasty Procedure and its benefits for treatement of bone marrow lesions
- MRI assessment of ACL reconstruction and cartilage health over time
- Utilization, safety and effectiveness of regional anesthesia for ACL surgery and clnical outcomes
Published Journal Articles and Abstracts:
Defea, K.A., Vaughn, Z.D., O’Bryan, E.M., Nishijima, D., Dery, O., Bunnett, N.W. “The Proliferative and Antiapoptotic Effects of Substance P are Facilitated by Formation
of a Beta- Arrestin-Dependent Scaffolding Complex.” Proceedings of the National Academy of the United States of America. Sept., 2000. 97 (20): 11086-11091.
Dery, Olivier; Grady, Eileen; Schmidlin, Fabien; Lovett, Michelle; Vaughn, Zackary; Bunnett, Nigel. “Heterologous Regulation of Signaling and Trafficking of the
Neurokinin-1 and Neurokinin-3 Receptors.” Regulatory Peptides. Oct., 2000. 94 (1-3): 29.
Schmidlin, Fabien; Defea, Kathryn; Dery, Olivier; Lovett, Michelle; Vaughn, Zackary; Grady, Eileen; Bunnett, Nigel. “Dynamin, B-arrestin and rab5a Mediated Trafficking
and Signalling of the Neurokinin-1 Receptor (NK-1R).” Regulatory Peptides. Oct., 2000. 94 (1-3): 17.
Schmidlin, Fabien; Dery, Olivier; Lovett, Michelle; Vaughn, Zackary; Defea, Kathryn; Grady, Eileen; Bunnett, Nigel. “Rab5A and Dynamin GTPases Mediate Substance P
(SP)-Induced Trafficking of the Neurokinin-1 Receptor (NK1R).” Gastroenterology. April, 2000. 118 (4): A180.
Vaughn, Zackary D., Johnson, Frank E., Beretvas, R. Ivan. “Laparoscopic Adrenalectomy for Conn’s Syndrome Complicated by Ipsilateral Pelvic Kidney.” Surgical
Endoscopy. Aug., 2004.18 (10): 1539.
Hsu AR, Vaughn Z, and Huddleston JI. Catastrophic Failure of a Porous-Coated Acetabular Cup due to Bead Shedding. A Case Report. Hip International. Oct-Dec 2009.
19(4):392-395.
Vaughn, Zackary D; Schmidt, Josh; Lindsey, Derek; Dragoo, Jason. “Biomechanical Evaluation of a one-stage ACL Revision Technique Using a Structural Bone Void
Filler for Femoral Fixation.” Arthroscopy Sept. 2009: 25(9)1101-1108.
Vaughn, Zackary D; Safran, Marc R. “Arthroscopic Femoral Osteoplasty/Chilectomy for CAM-type Femoroacetabular Impingement in the Athlete”. Sports Medicine and
Arthroscopy Review. 2010.
Dragoo, Jason; Miller, Matthew; Vaughn, Zackary; Handley, Elizabeth. “Resoration of Normal Knee Volume Using Selected Arthroscopic Releases.” Amer J of Sports Med
2010.
Safran, MR; Lopomo, N; Zaffagnini, S; Vaughn, ZD; Lindsey, DP; Gold, G; Bignozzi, S; Giordano, G;Marcacci, M. “In Vitro Analysis of Peri-Articular Soft Tissues Passive
Constraining Effect on Hip Kinematics and Joint Stability. Knee Surg Sports Traumatol Arthrosc. June 2012.
Tse, BK; Vaughn, ZD; Lindsey, DP; Dragoo, JL. “Evaluation of a one-stage ACL revision technique using bone void filler after cyclic loading.” Knee. Aug 2012; 19 (4).
Conference Presentations of Published Abstracts
(poster or podium by Vaughn or co-author):
Defea, K.A., Vaughn, Z.D., Dery, O., Bunnett, N.W. “B-Arrestin-Dependent Endocytosis of the Neurokinin 1 Receptor (NK1R) is Required for Activation of P42/44 MAP
Kinases.” Gastroenterology. April, 2000. 118 (4): A87.
Digestive Disease Week (DDW) and the 101st Annual Meeting of the American
Gastroenterological Association (AGA).
San Diego, California, May 2000
Poster Presented by Vaughn
Vaughn Z.D., Johnson, F.E., Beretvas, R.I. “Conn’s Syndrome Treated with Laparoscopic Adrenalectomy Complicated by Ipsilateral Congenital Pelvic Kidney.” Surgical
Endoscopy. March 2003. 17 (Suppl): S287.
Society of American Gastrointestinal Endoscopic Surgeons (SAGES).
Los Angeles, California, March 2003
Poster Presented by Vaughn
Beretvas, R. Ivan, Vaughn, Zackary D., Johnson, Frank E. “Laparoscopic Adrenalectomy with Ipsilateral Pelvic Kidney.”
(Training Video) American College of Surgeons; the 89th Clinical Congress
Chicago, Illinois, October 2003.
Presented by Beretvas
Safran, Marc; Zaffagnini, Stephano; Lopomo, Nicoli; Vaughn, Zackary; Lindsey, Derek; Gold, Garry et al. “The Influence of Soft Tissues on Hip Joint Kinematics: An In
Vitro Computer Assisted Anaylsis.”
Orthopaedic Research Society, 55th Annual Meeting
Las Vegas, Nevada, February 2009
Presented by Safran
Podium Presentations and Lectures:
“Hip arthroscopy and the Acetabular Labrum.”
Stanford University Department of Orthopeadic Surgery GRAND ROUNDS
Palo Alto, California, March 2008
“Revision ACL Reconstructions: A biomechanical evaluation of fixation strength and a novel technique for one-stage revisions.”
Northern California Chapter of the Western Orthopaedic Association
Sonoma, California, November 2007
Winner Best Resident Research Paper
&
American Academy of Orthopaedic Surgeons (AAOS)
San Francisco, California February 2008
&
OREF Resident Research Symposium
University of California, San Francisco, April 2009
“Biomechanical Evaluation of a one-stage ACL Revision Technique Using a Structural Bone Void Filler for Femoral Fixation.”
Stanford University Department of Orthopaedic Surgery Disputation Day
Palo Alto, California June 2009
“Shoulder Pathology: Labral Injuries, SLAP Lesions, and Biceps Tendon Injury”
Stanford University Sports Medicine Conference Lecture Series
October 2007
“Groin pain in the Athlete”
Stanford University Sports Medicine Conference Lecture Series
August 2009
“Posterior Shoulder Instability”
Stanford University Sports Medicine Conference Lecture Series
October 2009
“Lis Franc Injuries and Tarsal Coalitions in Athletes”
Stanford University Sports Medicine Conference Lecture Series
December 2009
“Patellar Instability”
Stanford University Sports Medicine Conference Lecture Series
February 2010
“Knee Ligament Injuries”
Stanford University
Physical Medicine / Rehabilitation Residency Educational Lecture Series
March 2010
“Partial Rotator Cuff Tears”
Stanford University Sports Medicine Conference Lecture Series
April 2010
“Spondyolysis and Spondylolisthesis in Athletes”
Stanford University Sports Medicine Conference Lecture Series
June 2010
“Common Hip Problems: Diagnosis and Treatment”
BEST Physical Therapy lecture series
July 2010
“Advances in the Treatment of Hip Pain with Arthroscopic Techniques”
Physical Therapy of Los Gatos
December 2010
“Advancements in the Treatment of Shoulder Injuries”
BEST Physical Therapy - Almaden Branch
February 2011
“High Tibial Osteotomy”
Stanford University Department of Orthopaedic Surgery Grand Rounds 2012
"Cartilage Restoration"
Stanford University Department of Orthopaedic Surgery Grand Rounds 2013
"Meniscus Repair - Is there a better method?"
Stanford University Department of Orthopaedic Surgery Grand Rounds 2015
Textbook Chapters:
Zackary D. Vaughn, MD and Marc R. Safran, MD. “Diagnostic Hip Arthroscopy: Set-up, Equipment, and Positioning – The Supine Approach”
In “Surgical Techniques in Hip Arthroscopy and Joint Preservation Surgery”; Elsevier Publication
Zackary D. Vaughn, MD; Ken Hunt, MD and Marc R. Safran, MD. “Ankle Arthroscopy.”
In “Arthroscopy Primer”, Elsevier Publication
Zackary D. Vaughn, MD; Marc R. Safran, MD. “Femoroacetabular Impingement”
In “Master Techniques in Orthopaedic Surgery – Sports Medicine”. Lippincott, William and Wilkins Publication
Research Grants Filed:Orthopaedic Research and Education Foundation:
OREF/DePuy Orthopaedic Resident Educational Grant. Evaluation of Wrist Kinematics in the Elite Golf Swing. Principal Investigator: Zackary D. Vaughn, MD. Mentor: Amy
Ladd, MD (Stanford University Hand And Upper Extremity Surgery)
PUBLICATIONS AND PRESENTATIONS

Zack Vaughn, MD
555 Knowles Drive Suite 201 Los Gatos, California, 95032 Office: (408) 866-6651 Fax: (408) 866-6681
zvaughn@stanford.edu
RECRUITING PATIENTS FOR NEW STUDY:
DID YOU JUST TEAR YOUR ACL??
THIS NEW STUDY IS ENROLLING PATIENTS THAT PRESENT WITHIN 1 WEEK OF AN ACL TEAR IN THE KNEE TO EVALUATE A CURRENT MEDICATION THAT DECREASES BLEDDING IN THE KNEE FROM THE INJURY AND MAY HAVE THE ABILITY TO REDUCE LONG TERM JOINT DAMAGE FROM THIS INJURY. ENROLLMENT IS OPTIONAL, BUT PLEASE CONTACT OUR OFFICE IMMEDIATELY (408-866-6651) IF YOU HAVE THIS ACUTE INJURY TO BE SEEN AS SOON AS POSSIBLE. YOU MAY ALSO CONTACT THE ACUTE ACL RESEARCH HOTLINE AT 650-721-7612.